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Jews constitute no more than 3 percent of the U.S. population but are 35 percent of American Nobel Prize winners. ... View MoreJews constitute no more than 3 percent of the U.S. population but are 35 percent of American Nobel Prize winners. As of 2017, Nobel Prizes had been awarded to 902 individuals worldwide. Though Jews are less than 2 percent of the world's population, 203, or 22.5 percent, of the Nobel Prizes were awarded to Jews. Proportionality would have created 18 Jewish Nobel laureates instead of an "unfair" 203. What should Congress and the United Nations do to "correct" such a disparity? Should the Nobel committees be charged with racism? 1. BioSight’s Astrabine “Trojan Horse” Technology BioSight, a medical technology startup, has been able to develop a technology that targets only cancerous cells, leaving healthy ones alone. Astrabine closely resembles a protein called asparagine that leukemia cells depend on and the cancer cells are fooled into self-destruction. According to Dr. Ruth Ben Yakar, this technology could become very important in the field of cancer treatment. “This really could be the cure for cancer,” she says. While BioSight’s “Trojan horse” chemo technology is currently being tested on leukemia patients, the company believes it will be effective in many other kinds of cancer as well. Read more about BioSight’s breakthrough: – Times of Israel – PR Newswire 2. Vaxil’s ImMucin Vaccine against 90% of Cancer Types Vaxil BioTheraputics has developed an immunotherapy vaccine that trains the immune system to attack cancerous cells. The vaccine is effective in the early stages of cancer detection and during remission. It will not help in the advanced stages of cancer. Clinical trials have so far showed that ImMucin triggered a response in 90% of cancer types. Read more about Vaxil’s breakthrough: – Medical Daily – NoCamels 3. Predicting the Spread of Cancer Most cancer-related deaths occur from metastases (secondary cancer) than by the primary tumor. Dr. Daphne Weihs, from Israel’s Institute of Technology, developed a method to predict the spread of cancer from one organ to another. According to Dr. Weihs, the practical concept is that “during or immediately after a biopsy or surgery on a malignant tumor, the system will enable the medical team to quantitatively evaluate the likelihood of the presence or development of tumor metastases in other organs, and to propose which organ or organs are involved. Such knowledge will make it possible to act at a very early stage to identify and curb these metastases and, moreover, to prevent the primary tumor from metastasizing further.” Read more about Dr. Daphne Weihs’ breakthrough: – Technion Israel Institute of Technology – New Journal of Physics (for in-depth explanation of the technology) 4. Nanotechnology Against Killer Cancers Glioblastoma multiforme (GBM) is one of the most aggressive and incurable forms of cancer. Professor Dan Peer of Quiet Therapeutics and his team at Tel Aviv University devised a technology using nanoparticles to transport drugs to target cancer sites while minimizing adverse effects. Restricted passages across the blood–brain barrier make the majority of potential drugs for the treatment of GBM ineffective. But with Peer’s nanotechnology, the drugs can be administered precisely to attack only the cancer cells, like a nanotech cancer bullet. The technology was tested successfully on ovarian cancer cells and is in the early stages of testing on brain tumors with promising results for the future. Read more about Prof. Dan Peer’s breakthrough: – ACS Publications – BioMed Microdevices Publication (for in-depth analysis of this nanotechnology) – Times of Israel 5. Immunotherapy Cocktail to Cure Melanoma and Terminal Cancer According to a study published in The New England Journal of Medicine, clinical trials on 945 patients with advanced melanoma skin cancer using a combination of immunotherapy drugs nivolumab and ipilimumab proved to cure 58% of the patients by shrinking or eliminating cancerous tumors. Prof. Jacob Schachter, head of the Ella Institute at Israel’s Sheba Medical Center, took part in developing this drug which was hailed by the scientific community as a major breakthrough in cancer research that can potentially replace chemotherapy to treat many types of cancer. Read more about Prof. Jacob Schachter’s breakthrough: – NoCamels – The New England Journal of Medicine 6. Nobel Prize Winner and Team Find Proteins to Suppress Cancer New research from the Haifa laboratory of Nobel Prize winner Prof. Aaron Ciechanover has uncovered two proteins that suppress cancer cell growth and development. Ciechanover, who is also the president of the Israel Cancer Society, notes that many more years are required “to establish the research and gain a solid understanding of the mechanisms behind the suppression of the tumors. The development of a drug based on this discovery is a possibility, although not a certainty, and the road to such a drug is long and far from simple.” Read more about Prof. Aaron Ciechanover’s breakthrough: – Nature Reviews Molecular Cell Biology – HaAretz (printed article) – Technion – Israel Institute of Technology – Cell 7. Hacking the Cancer’s Communication System Rony Seger from the Weizmann Institute of Science and his team developed a way to treat a number of cancers by blocking off messages from the nucleus of a cancer cell. By shutting off the information that creates cancerous mutations the spread of cancer can be halted. Read more about Rony Seger’s breakthrough: – The American Society for Cell Biology (and its Supplementary Information) – Journal of Cell Science – Nature Communications – NoCamels 8. Biop Medical Device to Provide Early Detection of Cervical Cancer Cervical cancer is the second most common cancer among women, and the #1 cancer killer of women in the developing world. According to Biop Medical, the startup company developed an innovative technology for the identification of cancerous and precancerous cells in epithelial tissues. The Biop system will enable point-of-care diagnosis of the entire cervix, generating a real-time map of the cervix. Immediately after testing, patients will receive a near-certain diagnosis, eliminating the prolonged waiting time and anxiety, associated with the current, inefficient process. This technology can reduce the time needed to diagnose one of the biggest killers of women – from weeks, to minutes. Read more about Biop Medical’s breakthrough technology: – Times of Israel Ginni Rometty, President and CEO of IBM, speaks about Biop Medical as being one of the cusps of the future of medicine, in her plenum speech at the Cleveland Clinic Summit. Heart Treatments 9. Study Advances Understanding of Heart Cells’ Regeneration If heart cells are damaged, e.g. by a heart attack, there is little than can be done to help repair and restore the heart. This is why heart disease is so fatal. A study conducted by Dr. Eldad Tzahor at the Weizmann Institute of Science suggests that a protein called ERBB2 may hold the key to regenerating heart cells. While the study was conducted on adult mice, the findings can prove to be a major breakthrough for heart disease treatments. Read more about Tzahor’s breakthrough: – Nature Cell Biology (and accompanying videos) – Cardiovascular Disease News – World Health – Weizmann Institute of Science – Weizmann Wonder Wander 10. Blue Light to Replace Pacemakers Using Optogenetics Technology Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light. The study was conducted at the laboratory of Professor Lior Gepstein from the Rappaport Faculty of Medicine and Research Institute at the Technion. If the biological pacemaker can be adapted for humans, it could help patients avoid many of the drawbacks of electrical pacemakers http://www.israelrising.com/18-israeli-medical-breakthroughs-of-2015-that-will-improve-medicine-your-health/

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Israel Changing Medicine Forever www.israelrising.com

May 11, 2025